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Ingredient

Curcumin (Turmeric Extract)

Promising

The polyphenol fraction of turmeric, often supplemented for joint comfort and antioxidant support.

How it works

Modulates NF-kappa-B and other inflammatory signalling pathways in vitro; oral bioavailability is low and depends on formulation.

Evidence

Multiple RCTs at well-formulated doses report joint-comfort outcomes; bioavailability is the limiting factor.

Studies

Daily et al., J Med Food, 2016
Meta-analysis of turmeric extracts for joint-comfort outcomes at standardized doses.
PubMed 27533649 ↗

One ingredient, one study, one product worth your money.

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