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Ingredient

Vitamin B12

Strong

An essential vitamin involved in red blood cell formation and energy metabolism.

How it works

Cofactor for methylmalonyl-CoA mutase and methionine synthase; deficiency is common in older adults and those on plant-based diets.

Evidence

Pharmacopoeia-grade evidence for adequacy; methylcobalamin or cyanocobalamin both studied.

Studies

  • Smith et al., Annu Rev Nutr, 2018

    Reviews B12 status and supplementation in vegetarians and older adults.

    PubMed 29400994

Top products

Sorted by effective monthly cost

Now Foods B12 1000 mg

Now Foods

Per serving
1000 mg
Studied midpoint
625 mg · 1/day

Effective cost

$0.11/day·$3/month

Nature Made B12 1000 mg

Nature Made

Per serving
1000 mg
Studied midpoint
625 mg · 1/day

Effective cost

$0.12/day·$4/month

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